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Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors

The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to existing antiretroviral therapies, emphasize the need to identify new HIV inhibitors. Here we performed a virtual screen of molecules from t...

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Detalles Bibliográficos
Autores principales: Tietjen, Ian, Ntie-Kang, Fidele, Mwimanzi, Philip, Onguéné, Pascal Amoa, Scull, Margaret A., Idowu, Thomas Oyebode, Ogundaini, Abiodun Oguntuga, Meva’a, Luc Mbaze, Abegaz, Berhanu M., Rice, Charles M., Andrae-Marobela, Kerstin, Brockman, Mark A., Brumme, Zabrina L., Fedida, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382154/
https://www.ncbi.nlm.nih.gov/pubmed/25830320
http://dx.doi.org/10.1371/journal.pone.0121099