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Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to existing antiretroviral therapies, emphasize the need to identify new HIV inhibitors. Here we performed a virtual screen of molecules from t...
Autores principales: | Tietjen, Ian, Ntie-Kang, Fidele, Mwimanzi, Philip, Onguéné, Pascal Amoa, Scull, Margaret A., Idowu, Thomas Oyebode, Ogundaini, Abiodun Oguntuga, Meva’a, Luc Mbaze, Abegaz, Berhanu M., Rice, Charles M., Andrae-Marobela, Kerstin, Brockman, Mark A., Brumme, Zabrina L., Fedida, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382154/ https://www.ncbi.nlm.nih.gov/pubmed/25830320 http://dx.doi.org/10.1371/journal.pone.0121099 |
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