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Notch1 Is Pan-Endothelial at the Onset of Flow and Regulated by Flow

Arteriovenous differentiation is a key event during vascular development and hemodynamic forces play an important role. Arteriovenous gene expression is present before the onset of flow, however it remains plastic and flow can alter arteriovenous identity. Notch signaling is especially important in...

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Detalles Bibliográficos
Autores principales: Jahnsen, Espen D., Trindade, Alexandre, Zaun, Hans C., Lehoux, Stéphanie, Duarte, António, Jones, Elizabeth A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382190/
https://www.ncbi.nlm.nih.gov/pubmed/25830332
http://dx.doi.org/10.1371/journal.pone.0122622