A Conserved Transcriptional Signature of Delayed Aging and Reduced Disease Vulnerability Is Partially Mediated by SIRT3

Aging is the most significant risk factor for a range of diseases, including many cancers, neurodegeneration, cardiovascular disease, and diabetes. Caloric restriction (CR) without malnutrition delays aging in diverse species, and therefore offers unique insights into age-related disease vulnerabili...

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Detalles Bibliográficos
Autores principales: Barger, Jamie L., Anderson, Rozalyn M., Newton, Michael A., da Silva, Cristina, Vann, James A., Pugh, Thomas D., Someya, Shinichi, Prolla, Tomas A., Weindruch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382298/
https://www.ncbi.nlm.nih.gov/pubmed/25830335
http://dx.doi.org/10.1371/journal.pone.0120738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382298/
https://www.ncbi.nlm.nih.gov/pubmed/25830335
http://dx.doi.org/10.1371/journal.pone.0120738

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