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Atomic accuracy models from 4.5 Å cryo-electron microscopy data with density-guided iterative local refinement
Direct electron detectors have made it possible to generate electron density maps at near atomic resolution using cryo-electron microscopy single particle reconstructions. Critical current questions include how best to build models into these maps, how high quality a map is required to generate an a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382417/ https://www.ncbi.nlm.nih.gov/pubmed/25707030 http://dx.doi.org/10.1038/nmeth.3286 |