RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm

Vascular inflammation is a major contributor to the severity of acute kidney injury. In the context of vasospasm-independent reperfusion injury we studied the potential anti-inflammatory role of the Gα-related RGS protein, RGS4. Transgenic RGS4 mice were resistant to 25 minute injury, although post-...

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Detalles Bibliográficos
Autores principales: Pang, Paul, Jin, Xiaohua, Proctor, Brandon M., Farley, Michelle, Roy, Nilay, Chin, Matthew S., von Andrian, Ulrich H., Vollmann, Elisabeth, Perro, Mario, Hoffman, Ryan J., Chung, Joseph, Chauhan, Nikita, Mistri, Murti, Muslin, Anthony J., Bonventre, Joseph V., Siedlecki, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382433/
https://www.ncbi.nlm.nih.gov/pubmed/25469849
http://dx.doi.org/10.1038/ki.2014.364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382433/
https://www.ncbi.nlm.nih.gov/pubmed/25469849
http://dx.doi.org/10.1038/ki.2014.364

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