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RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm
Vascular inflammation is a major contributor to the severity of acute kidney injury. In the context of vasospasm-independent reperfusion injury we studied the potential anti-inflammatory role of the Gα-related RGS protein, RGS4. Transgenic RGS4 mice were resistant to 25 minute injury, although post-...
Autores principales: | Pang, Paul, Jin, Xiaohua, Proctor, Brandon M., Farley, Michelle, Roy, Nilay, Chin, Matthew S., von Andrian, Ulrich H., Vollmann, Elisabeth, Perro, Mario, Hoffman, Ryan J., Chung, Joseph, Chauhan, Nikita, Mistri, Murti, Muslin, Anthony J., Bonventre, Joseph V., Siedlecki, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382433/ https://www.ncbi.nlm.nih.gov/pubmed/25469849 http://dx.doi.org/10.1038/ki.2014.364 |
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