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Inverse Agonistic Action of 3-Iodothyronamine at the Human Trace Amine-Associated Receptor 5
Objective Application of 3-iodothyronamine (3-T(1)AM) results in decreased body temperature and body weight in rodents. The trace amine-associated receptor (TAAR) 1, a family A G protein-coupled receptor, is a target of 3-T(1)AM. However, 3-T(1)AM effects still persist in mTaar1 knockout mice, which...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382497/ https://www.ncbi.nlm.nih.gov/pubmed/25706283 http://dx.doi.org/10.1371/journal.pone.0117774 |