Cargando…

A critical base pair in k-turns that confers folding characteristics and correlates with biological function

Kink turns (k-turns) are widespread elements in RNA that mediate tertiary contacts by kinking the helical axis. We have found that the ability of k-turns to undergo ion-induced folding is conferred by a single base pair that follows the conserved A·G pairs, that is, the 3b·3n position. A Watson–Cric...

Descripción completa

Detalles Bibliográficos
Autores principales: McPhee, Scott A., Huang, Lin, Lilley, David M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382518/
https://www.ncbi.nlm.nih.gov/pubmed/25351101
http://dx.doi.org/10.1038/ncomms6127