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Dysregulated choline metabolism in T-cell lymphoma: role of choline kinase-α and therapeutic targeting

Cancer cells have distinct metabolomic profile. Metabolic enzymes regulate key oncogenic signaling pathways and have an essential role on tumor progression. Here, serum metabolomic analysis was performed in 45 patients with T-cell lymphoma (TCL) and 50 healthy volunteers. The results showed that dys...

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Detalles Bibliográficos
Autores principales: Xiong, J, Bian, J, Wang, L, Zhou, J-Y, Wang, Y, Zhao, Y, Wu, L-L, Hu, J-J, Li, B, Chen, S-J, Yan, C, Zhao, W-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382653/
https://www.ncbi.nlm.nih.gov/pubmed/25768400
http://dx.doi.org/10.1038/bcj.2015.10