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Dysregulated choline metabolism in T-cell lymphoma: role of choline kinase-α and therapeutic targeting
Cancer cells have distinct metabolomic profile. Metabolic enzymes regulate key oncogenic signaling pathways and have an essential role on tumor progression. Here, serum metabolomic analysis was performed in 45 patients with T-cell lymphoma (TCL) and 50 healthy volunteers. The results showed that dys...
Autores principales: | Xiong, J, Bian, J, Wang, L, Zhou, J-Y, Wang, Y, Zhao, Y, Wu, L-L, Hu, J-J, Li, B, Chen, S-J, Yan, C, Zhao, W-L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382653/ https://www.ncbi.nlm.nih.gov/pubmed/25768400 http://dx.doi.org/10.1038/bcj.2015.10 |
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