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A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia

Relevant preclinical mouse models are crucial to screen new therapeutic agents for acute myeloid leukemia (AML). Current in vivo models based on the use of patient samples are not easy to establish and manipulate in the laboratory. Our objective was to develop robust xenograft models of human AML us...

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Detalles Bibliográficos
Autores principales: Saland, E, Boutzen, H, Castellano, R, Pouyet, L, Griessinger, E, Larrue, C, de Toni, F, Scotland, S, David, M, Danet-Desnoyers, G, Vergez, F, Barreira, Y, Collette, Y, Récher, C, Sarry, J-E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382660/
https://www.ncbi.nlm.nih.gov/pubmed/25794133
http://dx.doi.org/10.1038/bcj.2015.19