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A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia
Relevant preclinical mouse models are crucial to screen new therapeutic agents for acute myeloid leukemia (AML). Current in vivo models based on the use of patient samples are not easy to establish and manipulate in the laboratory. Our objective was to develop robust xenograft models of human AML us...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382660/ https://www.ncbi.nlm.nih.gov/pubmed/25794133 http://dx.doi.org/10.1038/bcj.2015.19 |