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Total synthesis of clostrubin

Clostrubin is a potent antibiotic against methicillin- and vancomycin-resistant bacteria that was isolated from a strictly anaerobic bacterium Clostridium beijerinckii in 2014. This polyphenol possesses a fully substituted arene moiety on its pentacyclic scaffold, which poses a considerable challeng...

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Detalles Bibliográficos
Autores principales: Yang, Ming, Li, Jian, Li, Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382683/
https://www.ncbi.nlm.nih.gov/pubmed/25759087
http://dx.doi.org/10.1038/ncomms7445