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Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins
Hydration water is the natural matrix of biological macromolecules and is essential for their activity in cells. The coupling between water and protein dynamics has been intensively studied, yet it remains controversial. Here we combine protein perdeuteration, neutron scattering and molecular dynami...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382692/ https://www.ncbi.nlm.nih.gov/pubmed/25774711 http://dx.doi.org/10.1038/ncomms7490 |