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Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins

Hydration water is the natural matrix of biological macromolecules and is essential for their activity in cells. The coupling between water and protein dynamics has been intensively studied, yet it remains controversial. Here we combine protein perdeuteration, neutron scattering and molecular dynami...

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Detalles Bibliográficos
Autores principales: Schirò, Giorgio, Fichou, Yann, Gallat, Francois-Xavier, Wood, Kathleen, Gabel, Frank, Moulin, Martine, Härtlein, Michael, Heyden, Matthias, Colletier, Jacques-Philippe, Orecchini, Andrea, Paciaroni, Alessandro, Wuttke, Joachim, Tobias, Douglas J., Weik, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382692/
https://www.ncbi.nlm.nih.gov/pubmed/25774711
http://dx.doi.org/10.1038/ncomms7490