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Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota

Obesity is a pandemic disease associated with many metabolic alterations and involves several organs and systems. The endocannabinoid system (ECS) appears to be a key regulator of energy homeostasis and metabolism. Here we show that specific deletion of the ECS synthesizing enzyme, NAPE-PLD, in adip...

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Detalles Bibliográficos
Autores principales: Geurts, Lucie, Everard, Amandine, Van Hul, Matthias, Essaghir, Ahmed, Duparc, Thibaut, Matamoros, Sébastien, Plovier, Hubert, Castel, Julien, Denis, Raphael G. P., Bergiers, Marie, Druart, Céline, Alhouayek, Mireille, Delzenne, Nathalie M., Muccioli, Giulio G., Demoulin, Jean-Baptiste, Luquet, Serge, Cani, Patrice D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382707/
https://www.ncbi.nlm.nih.gov/pubmed/25757720
http://dx.doi.org/10.1038/ncomms7495