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CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
Summary: CRISPRdirect is a simple and functional web server for selecting rational CRISPR/Cas targets from an input sequence. The CRISPR/Cas system is a promising technique for genome engineering which allows target-specific cleavage of genomic DNA guided by Cas9 nuclease in complex with a guide RNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382898/ https://www.ncbi.nlm.nih.gov/pubmed/25414360 http://dx.doi.org/10.1093/bioinformatics/btu743 |