Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

INTRODUCTION: Medulloblastoma (MB) is the most frequent malignant brain tumor in children. Four subgroups with distinct genetic, epigenetic and clinical characteristics have been identified. Survival remains particularly poor in patients with Group 3 tumors harbouring a MYC amplification. We herein...

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Detalles Bibliográficos
Autores principales: Ecker, Jonas, Oehme, Ina, Mazitschek, Ralph, Korshunov, Andrey, Kool, Marcel, Hielscher, Thomas, Kiss, Judit, Selt, Florian, Konrad, Carina, Lodrini, Marco, Deubzer, Hedwig E, von Deimling, Andreas, Kulozik, Andreas E, Pfister, Stefan M, Witt, Olaf, Milde, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382927/
https://www.ncbi.nlm.nih.gov/pubmed/25853389
http://dx.doi.org/10.1186/s40478-015-0201-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382927/
https://www.ncbi.nlm.nih.gov/pubmed/25853389
http://dx.doi.org/10.1186/s40478-015-0201-7

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