Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder

BACKGROUND: Bipolar affective disorder (BP) is a common, highly heritable psychiatric disorder characterized by periods of depression and mania. Using dense SNP genotype data, we characterized CNVs in 388 members of an Old Order Amish Pedigree with bipolar disorder. We identified CNV regions arising...

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Detalles Bibliográficos
Autores principales: Kember, Rachel L, Georgi, Benjamin, Bailey-Wilson, Joan E, Stambolian, Dwight, Paul, Steven M, Bućan, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382929/
https://www.ncbi.nlm.nih.gov/pubmed/25887117
http://dx.doi.org/10.1186/s12863-015-0184-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382929/
https://www.ncbi.nlm.nih.gov/pubmed/25887117
http://dx.doi.org/10.1186/s12863-015-0184-1

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