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Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder
BACKGROUND: Bipolar affective disorder (BP) is a common, highly heritable psychiatric disorder characterized by periods of depression and mania. Using dense SNP genotype data, we characterized CNVs in 388 members of an Old Order Amish Pedigree with bipolar disorder. We identified CNV regions arising...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382929/ https://www.ncbi.nlm.nih.gov/pubmed/25887117 http://dx.doi.org/10.1186/s12863-015-0184-1 |