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Enterohemorrhagic Escherichia coli senses low biotin status in the large intestine for colonization and infection

Enterohemorrhagic Escherichia coli (EHEC) is an important foodborne pathogen that infects humans by colonizing the large intestine. Here we identify a virulence-regulating pathway in which the biotin protein ligase BirA signals to the global regulator Fur, which in turn activates LEE (locus of enter...

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Detalles Bibliográficos
Autores principales: Yang, Bin, Feng, Lu, Wang, Fang, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382993/
https://www.ncbi.nlm.nih.gov/pubmed/25791315
http://dx.doi.org/10.1038/ncomms7592