Cargando…

SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation

Short interspersed nuclear elements (SINEs), such as Alu, spread by retrotransposition, which requires their transcripts to be copied into DNA and then inserted into new chromosomal sites. This can lead to genetic damage through insertional mutagenesis and chromosomal rearrangements between non-alle...

Descripción completa

Detalles Bibliográficos
Autores principales: Varshney, Dhaval, Vavrova-Anderson, Jana, Oler, Andrew J., Cowling, Victoria H., Cairns, Bradley R., White, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382998/
https://www.ncbi.nlm.nih.gov/pubmed/25798578
http://dx.doi.org/10.1038/ncomms7569