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SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation
Short interspersed nuclear elements (SINEs), such as Alu, spread by retrotransposition, which requires their transcripts to be copied into DNA and then inserted into new chromosomal sites. This can lead to genetic damage through insertional mutagenesis and chromosomal rearrangements between non-alle...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382998/ https://www.ncbi.nlm.nih.gov/pubmed/25798578 http://dx.doi.org/10.1038/ncomms7569 |