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Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase

Histone modifiers play essential roles in controlling transcription and organizing eukaryotic genomes into functional domains. Here, we show that Set1, the catalytic subunit of the highly conserved Set1C/COMPASS complex responsible for histone H3K4 methylation (H3K4me), behaves as a repressor of the...

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Detalles Bibliográficos
Autores principales: Lorenz, David R, Meyer, Lauren F, Grady, Patrick J R, Meyer, Michelle M, Cam, Hugh P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383021/
https://www.ncbi.nlm.nih.gov/pubmed/25497836
http://dx.doi.org/10.7554/eLife.04506