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Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase
Histone modifiers play essential roles in controlling transcription and organizing eukaryotic genomes into functional domains. Here, we show that Set1, the catalytic subunit of the highly conserved Set1C/COMPASS complex responsible for histone H3K4 methylation (H3K4me), behaves as a repressor of the...
Autores principales: | Lorenz, David R, Meyer, Lauren F, Grady, Patrick J R, Meyer, Michelle M, Cam, Hugh P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383021/ https://www.ncbi.nlm.nih.gov/pubmed/25497836 http://dx.doi.org/10.7554/eLife.04506 |
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