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Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis

Because photodynamic therapy (PDT) alone is not always effective as an anticancer treatment, PDT is combined with other anticancer agents for improved efficacy. The clinically-relevant fenretinide [N-(4-hydroxyphenyl) retinamide; 4HPR], was combined with the silicon phthalocyanine photosensitizer Pc...

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Detalles Bibliográficos
Autores principales: BOPPANA, NITHIN B., STOCHAJ, URSULA, KODIHA, MOHAMED, BIELAWSKA, ALICJA, BIELAWSKI, JACEK, PIERCE, JASON S., KORBELIK, MLADEN, SEPAROVIC, DUSKA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383026/
https://www.ncbi.nlm.nih.gov/pubmed/25739041
http://dx.doi.org/10.3892/ijo.2015.2909