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Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures

Epithelial-to-mesenchymal transition (EMT) confers stem cell-like phenotype and more motile properties to carcinoma cells. During EMT, the expression of E-cadherin decreases, resulting in loss of cell-cell adhesion and increased migration. Expression of Twist1 and other pleiotropic transcription fac...

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Detalles Bibliográficos
Autores principales: COSTABILE, VALERIA, DURATURO, FRANCESCA, DELRIO, PAOLO, REGA, DANIELA, PACE, UGO, LICCARDO, RAFFAELLA, ROSSI, GIOVANNI BATTISTA, GENESIO, RITA, NITSCH, LUCIO, IZZO, PAOLA, DE ROSA, MARINA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383027/
https://www.ncbi.nlm.nih.gov/pubmed/25738332
http://dx.doi.org/10.3892/ijo.2015.2911