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Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures
Epithelial-to-mesenchymal transition (EMT) confers stem cell-like phenotype and more motile properties to carcinoma cells. During EMT, the expression of E-cadherin decreases, resulting in loss of cell-cell adhesion and increased migration. Expression of Twist1 and other pleiotropic transcription fac...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383027/ https://www.ncbi.nlm.nih.gov/pubmed/25738332 http://dx.doi.org/10.3892/ijo.2015.2911 |