Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cells

Transient receptor potential, melastatin-2 (TRPM2) is a plasma membrane cation channel with important roles in sensory functions and promoting cell death. However, we demonstrated here that TRPM2 was present in the nuclei of MCF-7 and MDA-MB-231 human breast adenocarcinoma cells, and its pharmacolog...

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Detalles Bibliográficos
Autores principales: HOPKINS, MANDI M., FENG, XIAOXING, LIU, MENGWEI, PARKER, LAUREN P., KOH, DAVID W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383028/
https://www.ncbi.nlm.nih.gov/pubmed/25760245
http://dx.doi.org/10.3892/ijo.2015.2919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383028/
https://www.ncbi.nlm.nih.gov/pubmed/25760245
http://dx.doi.org/10.3892/ijo.2015.2919

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