Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase

How different helicase families with a conserved catalytic ‘helicase core’ evolved to function on varied RNA and DNA substrates by diverse mechanisms remains unclear. In this study, we used Mss116, a yeast DEAD-box protein that utilizes ATP to locally unwind dsRNA, to investigate helicase specificit...

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Detalles Bibliográficos
Autores principales: Mallam, Anna L, Sidote, David J, Lambowitz, Alan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383044/
https://www.ncbi.nlm.nih.gov/pubmed/25497230
http://dx.doi.org/10.7554/eLife.04630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383044/
https://www.ncbi.nlm.nih.gov/pubmed/25497230
http://dx.doi.org/10.7554/eLife.04630

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