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High performance computing enabling exhaustive analysis of higher order single nucleotide polymorphism interaction in Genome Wide Association Studies

Genome-wide association studies (GWAS) are a common approach for systematic discovery of single nucleotide polymorphisms (SNPs) which are associated with a given disease. Univariate analysis approaches commonly employed may miss important SNP associations that only appear through multivariate analys...

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Detalles Bibliográficos
Autores principales: Goudey, Benjamin, Abedini, Mani, Hopper, John L, Inouye, Michael, Makalic, Enes, Schmidt, Daniel F, Wagner, John, Zhou, Zeyu, Zobel, Justin, Reumann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383059/
https://www.ncbi.nlm.nih.gov/pubmed/25870758
http://dx.doi.org/10.1186/2047-2501-3-S1-S3