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Understanding the molecular basis of EGFR kinase domain/MIG-6 peptide recognition complex using computational analyses
BACKGROUND: Epidermal growth factor receptor (EGFR) signalling plays a major role in biological processes, including cell proliferation, differentiation and survival. Since the over-expression of EGFR causes human cancers, EGFR is an attractive drug target. A tumor suppressor endogenous protein, MIG...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383062/ https://www.ncbi.nlm.nih.gov/pubmed/25885222 http://dx.doi.org/10.1186/s12859-015-0528-x |