Understanding the molecular basis of EGFR kinase domain/MIG-6 peptide recognition complex using computational analyses

BACKGROUND: Epidermal growth factor receptor (EGFR) signalling plays a major role in biological processes, including cell proliferation, differentiation and survival. Since the over-expression of EGFR causes human cancers, EGFR is an attractive drug target. A tumor suppressor endogenous protein, MIG...

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Detalles Bibliográficos
Autores principales: Moonrin, Ninnutt, Songtawee, Napat, Rattanabunyong, Siriluk, Chunsrivirot, Surasuk, Mokmak, Wanwimon, Tongsima, Sissades, Choowongkomon, Kiattawee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383062/
https://www.ncbi.nlm.nih.gov/pubmed/25885222
http://dx.doi.org/10.1186/s12859-015-0528-x

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