High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

Microtubule-based transport by the kinesin motors, powered by ATP hydrolysis, is essential for a wide range of vital processes in eukaryotes. We obtained insight into this process by developing atomic models for no-nucleotide and ATP states of the monomeric kinesin motor domain on microtubules from...

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Detalles Bibliográficos
Autores principales: Shang, Zhiguo, Zhou, Kaifeng, Xu, Chen, Csencsits, Roseann, Cochran, Jared C, Sindelar, Charles V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383081/
https://www.ncbi.nlm.nih.gov/pubmed/25415053
http://dx.doi.org/10.7554/eLife.04686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383081/
https://www.ncbi.nlm.nih.gov/pubmed/25415053
http://dx.doi.org/10.7554/eLife.04686

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