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High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation
Microtubule-based transport by the kinesin motors, powered by ATP hydrolysis, is essential for a wide range of vital processes in eukaryotes. We obtained insight into this process by developing atomic models for no-nucleotide and ATP states of the monomeric kinesin motor domain on microtubules from...
Autores principales: | Shang, Zhiguo, Zhou, Kaifeng, Xu, Chen, Csencsits, Roseann, Cochran, Jared C, Sindelar, Charles V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383081/ https://www.ncbi.nlm.nih.gov/pubmed/25415053 http://dx.doi.org/10.7554/eLife.04686 |
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