Metronomic Gemcitabine in Combination with Sunitinib Inhibits Multisite Metastasis and Increases Survival in an Orthotopic Model of Pancreatic Cancer

Metronomic chemotherapy suppresses growth of primary tumors and established metastases. However, its effect on metastatic progression is essentially unknown. We report the treatment of a metastatically competent model of pancreatic cancer with metronomic gemcitabine and sunitinib. Mice with orthotop...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran Cao, Hop S., Bouvet, Michael, Kaushal, Sharmeela, Keleman, Alex, Romney, Eric, Kim, Ginna, Fruehauf, John, Imagawa, David K., Hoffman, Robert M., Katz, Matthew H.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383085/
https://www.ncbi.nlm.nih.gov/pubmed/20606044
http://dx.doi.org/10.1158/1535-7163.MCT-10-0201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383085/
https://www.ncbi.nlm.nih.gov/pubmed/20606044
http://dx.doi.org/10.1158/1535-7163.MCT-10-0201

Ejemplares similares