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Metronomic Gemcitabine in Combination with Sunitinib Inhibits Multisite Metastasis and Increases Survival in an Orthotopic Model of Pancreatic Cancer
Metronomic chemotherapy suppresses growth of primary tumors and established metastases. However, its effect on metastatic progression is essentially unknown. We report the treatment of a metastatically competent model of pancreatic cancer with metronomic gemcitabine and sunitinib. Mice with orthotop...
Autores principales: | Tran Cao, Hop S., Bouvet, Michael, Kaushal, Sharmeela, Keleman, Alex, Romney, Eric, Kim, Ginna, Fruehauf, John, Imagawa, David K., Hoffman, Robert M., Katz, Matthew H.G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383085/ https://www.ncbi.nlm.nih.gov/pubmed/20606044 http://dx.doi.org/10.1158/1535-7163.MCT-10-0201 |
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