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The evolution of drug resistance in clinical isolates of Candida albicans

Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading to drug resistance. Studies in clinical isolates have implicated multiple mechanism...

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Detalles Bibliográficos
Autores principales: Ford, Christopher B, Funt, Jason M, Abbey, Darren, Issi, Luca, Guiducci, Candace, Martinez, Diego A, Delorey, Toni, Li, Bi yu, White, Theodore C, Cuomo, Christina, Rao, Reeta P, Berman, Judith, Thompson, Dawn A, Regev, Aviv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383195/
https://www.ncbi.nlm.nih.gov/pubmed/25646566
http://dx.doi.org/10.7554/eLife.00662