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Structure of a low-population intermediate state in the release of an enzyme product

Enzymes can increase the rate of biomolecular reactions by several orders of magnitude. Although the steps of substrate capture and product release are essential in the enzymatic process, complete atomic-level descriptions of these steps are difficult to obtain because of the transient nature of the...

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Detalles Bibliográficos
Autores principales: De Simone, Alfonso, Aprile, Francesco A, Dhulesia, Anne, Dobson, Christopher M, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383205/
https://www.ncbi.nlm.nih.gov/pubmed/25575179
http://dx.doi.org/10.7554/eLife.02777