Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

Eukaryotic cells rapidly reduce protein synthesis in response to various stress conditions. This can be achieved by the phosphorylation-mediated inactivation of a key translation initiation factor, eukaryotic initiation factor 2 (eIF2). However, the persistent translation of certain mRNAs is require...

Descripción completa

Detalles Bibliográficos
Autores principales: Andreev, Dmitry E, O'Connor, Patrick BF, Fahey, Ciara, Kenny, Elaine M, Terenin, Ilya M, Dmitriev, Sergey E, Cormican, Paul, Morris, Derek W, Shatsky, Ivan N, Baranov, Pavel V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383229/
https://www.ncbi.nlm.nih.gov/pubmed/25621764
http://dx.doi.org/10.7554/eLife.03971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383229/
https://www.ncbi.nlm.nih.gov/pubmed/25621764
http://dx.doi.org/10.7554/eLife.03971

Ejemplares similares