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Scavenger Receptor SREC-I Mediated Entry of TLR4 into Lipid Microdomains and Triggered Inflammatory Cytokine Release in RAW 264.7 Cells upon LPS Activation

Scavenger receptor associated with endothelial cells I (SREC-I) was shown to be expressed in immune cells and to play a role in the endocytosis of peptides and antigen presentation. As our previous studies indicated that SREC-I required intact Toll-like receptor 4 (TLR4) expression for its functions...

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Detalles Bibliográficos
Autores principales: Murshid, Ayesha, Gong, Jianlin, Prince, Thomas, Borges, Thiago J., Calderwood, Stuart K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383338/
https://www.ncbi.nlm.nih.gov/pubmed/25836976
http://dx.doi.org/10.1371/journal.pone.0122529