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Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli

Intracellular thiols like L-cystine and L-cystine play a critical role in the regulation of cellular processes. Here we show that Escherichia coli has two L-cystine transporters, the symporter YdjN and the ATP-binding cassette importer FliY-YecSC. These proteins import L-cystine, an oxidized product...

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Detalles Bibliográficos
Autores principales: Ohtsu, Iwao, Kawano, Yusuke, Suzuki, Marina, Morigasaki, Susumu, Saiki, Kyohei, Yamazaki, Shunsuke, Nonaka, Gen, Takagi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383340/
https://www.ncbi.nlm.nih.gov/pubmed/25837721
http://dx.doi.org/10.1371/journal.pone.0120619