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Modeling Transmembrane Domain Dimers/Trimers of Plexin Receptors: Implications for Mechanisms of Signal Transmission across the Membrane

Single-pass transmembrane (TM) receptors transmit signals across lipid bilayers by helix association or by configurational changes within preformed dimers. The structure determination for such TM regions is challenging and has mostly been accomplished by NMR spectroscopy. Recently, the computational...

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Detalles Bibliográficos
Autores principales: Zhang, Liqun, Polyansky, Anton, Buck, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383379/
https://www.ncbi.nlm.nih.gov/pubmed/25837709
http://dx.doi.org/10.1371/journal.pone.0121513