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Placing Ion Channels into a Signaling Network of T Cells: From Maturing Thymocytes to Healthy T Lymphocytes or Leukemic T Lymphoblasts

T leukemogenesis is a multistep process, where the genetic errors during T cell maturation cause the healthy progenitor to convert into the leukemic precursor that lost its ability to differentiate but possesses high potential for proliferation, self-renewal, and migration. A new misdirecting “leuke...

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Detalles Bibliográficos
Autores principales: Dobrovinskaya, Oxana, Delgado-Enciso, Iván, Quintero-Castro, Laura Johanna, Best-Aguilera, Carlos, Rojas-Sotelo, Rocío Monserrat, Pottosin, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383400/
https://www.ncbi.nlm.nih.gov/pubmed/25866806
http://dx.doi.org/10.1155/2015/750203