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Interleukin-18 Increases TLR4 and Mannose Receptor Expression and Modulates Cytokine Production in Human Monocytes

Interleukin-18 is a proinflammatory cytokine belonging to the interleukin-1 family of cytokines. This cytokine exerts many unique biological and immunological effects. To explore the role of IL-18 in inflammatory innate immune responses, we investigated its impact on expression of two toll-like rece...

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Detalles Bibliográficos
Autores principales: Dias-Melicio, Luciane Alarcão, Fernandes, Reginaldo Keller, Rodrigues, Daniela Ramos, Golim, Marjorie Assis, Soares, Angela Maria Victoriano Campos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383410/
https://www.ncbi.nlm.nih.gov/pubmed/25873755
http://dx.doi.org/10.1155/2015/236839