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Liver Injury Indicating Fatty Liver but Not Serologic NASH Marker Improves under Metformin Treatment in Polycystic Ovary Syndrome

Objective. Polycystic ovary syndrome (PCOS) is associated with obesity and insulin resistance (IR), key features of nonalcoholic steatohepatitis (NASH). Cytokeratin 18 fragments (M30) have been established as a serum marker for NASH. The insulin sensitizer metformin improves hepatic IR. This study e...

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Detalles Bibliográficos
Autores principales: Tan, Susanne, Vollmar, Nils, Benson, Sven, Sowa, Jan-Peter, Bechmann, Lars P., Gerken, Guido, Fuhrer, Dagmar, Canbay, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383456/
https://www.ncbi.nlm.nih.gov/pubmed/25873949
http://dx.doi.org/10.1155/2015/254169