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Insulin-Like Growth Factor System in Cancer: Novel Targeted Therapies

Insulin-like growth factors (IGFs) are essential for growth and survival that suppress apoptosis and promote cell cycle progression, angiogenesis, and metastatic activities in various cancers. The IGFs actions are mediated through the IGF-1 receptor that is involved in cell transformation induced by...

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Detalles Bibliográficos
Autores principales: Brahmkhatri, Varsha P., Prasanna, Chinmayi, Atreya, Hanudatta S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383470/
https://www.ncbi.nlm.nih.gov/pubmed/25866791
http://dx.doi.org/10.1155/2015/538019