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Insulin-Like Growth Factor System in Cancer: Novel Targeted Therapies
Insulin-like growth factors (IGFs) are essential for growth and survival that suppress apoptosis and promote cell cycle progression, angiogenesis, and metastatic activities in various cancers. The IGFs actions are mediated through the IGF-1 receptor that is involved in cell transformation induced by...
Autores principales: | Brahmkhatri, Varsha P., Prasanna, Chinmayi, Atreya, Hanudatta S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383470/ https://www.ncbi.nlm.nih.gov/pubmed/25866791 http://dx.doi.org/10.1155/2015/538019 |
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