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Physiological Impact of Abnormal Lipoxin A(4) Production on Cystic Fibrosis Airway Epithelium and Therapeutic Potential

Lipoxin A(4) has been described as a major signal for the resolution of inflammation and is abnormally produced in the lungs of patients with cystic fibrosis (CF). In CF, the loss of chloride transport caused by the mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) cha...

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Detalles Bibliográficos
Autores principales: Higgins, Gerard, Ringholz, Fiona, Buchanan, Paul, McNally, Paul, Urbach, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383482/
https://www.ncbi.nlm.nih.gov/pubmed/25866809
http://dx.doi.org/10.1155/2015/781087