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Computational Selection of RNA Aptamer against Angiopoietin-2 and Experimental Evaluation

Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin-2 (Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of this study was to introduce a computational simulation approach to screen aptamers with high binding ability for A...

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Detalles Bibliográficos
Autores principales: Hu, Wen-Pin, Kumar, Jangam Vikram, Huang, Chun-Jen, Chen, Wen-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383501/
https://www.ncbi.nlm.nih.gov/pubmed/25866800
http://dx.doi.org/10.1155/2015/658712