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Computational Selection of RNA Aptamer against Angiopoietin-2 and Experimental Evaluation
Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin-2 (Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of this study was to introduce a computational simulation approach to screen aptamers with high binding ability for A...
Autores principales: | Hu, Wen-Pin, Kumar, Jangam Vikram, Huang, Chun-Jen, Chen, Wen-Yih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383501/ https://www.ncbi.nlm.nih.gov/pubmed/25866800 http://dx.doi.org/10.1155/2015/658712 |
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