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Hybrid Spreading Mechanisms and T Cell Activation Shape the Dynamics of HIV-1 Infection
HIV-1 can disseminate between susceptible cells by two mechanisms: cell-free infection following fluid-phase diffusion of virions and by highly-efficient direct cell-to-cell transmission at immune cell contacts. The contribution of this hybrid spreading mechanism, which is also a characteristic of s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383537/ https://www.ncbi.nlm.nih.gov/pubmed/25837979 http://dx.doi.org/10.1371/journal.pcbi.1004179 |