Association between P16(INK4a) Promoter Methylation and HNSCC: A Meta-Analysis of 21 Published Studies

BACKGROUND: The p16(INK4a) is an important tumor suppressor gene (TSG) and aberrant methylation of promoter is known to be a major inactivation mechanism of the tumor suppressor and tumor-related genes. Aberrant TSG methylation was considered an important epigenetic silencing mechanism in the progre...

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Detalles Bibliográficos
Autores principales: Shi, Hao, Chen, Xiong, Lu, Cheng, Gu, Changmei, Jiang, Hongwei, Meng, RuiWei, Niu, Xun, Huang, Yangxin, Lu, Meixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383544/
https://www.ncbi.nlm.nih.gov/pubmed/25835498
http://dx.doi.org/10.1371/journal.pone.0122302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383544/
https://www.ncbi.nlm.nih.gov/pubmed/25835498
http://dx.doi.org/10.1371/journal.pone.0122302

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